![]() ![]() Patients who had a highest recorded MAP in the range 95–104 mmHg had the lowest associated mortality. Patients who had a lowest recorded MAP in the range 60–63 mmHg had the lowest associated mortality. Both hypotension and hypertension were associated with increased mortality. The median lowest and highest MAP and SBP were similar in survivors and non-survivors. ResultsĪ total of 32,349 patients were included in the analysis. ![]() We report the adjusted odds ratio for associations between lowest and highest mean arterial pressure (MAP) and systolic blood pressure (SBP) in the first 24 h of ICU care and hospital mortality. Restricted cubic splines were created following adjustment for important prognostic variables. We conducted a retrospective analysis of OHCA patients included in the Intensive Care National Audit and Research Centre Case Mix Programme from 1 January 2010 to 31 December 2019. We hypothesised that exposure to hypotension and hypertension in the first 24 h in ICU would be associated with mortality following OHCA. However, the optimal blood pressure following OHCA is unknown. Current guidelines recommend avoiding hypotension. Hypotension following out-of-hospital cardiac arrest (OHCA) may cause secondary brain injury and increase mortality rates. ![]()
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